A simple and reproducible crystallization method for the preparation of 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid (febuxostat) polymorphic form-B via acetic acid solvate

Ch; ra Kant Belwal; Kaushik A. Joshi

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 3

A simple and reproducible crystallization method for the preparation of 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid (febuxostat) polymorphic form-B via acetic acid solvate

Abstract

A simple and reproducible crystallization method was developed for the synthesis of xanthine oxidase inhibitor febuxostat polymorphic form- B via acetic acid solvate.

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