A new synthesis of 2, 5-dibromo-3-[2-(2-methoxyethoxy) ethoxy]methylthiophene, which was prepared in good to high yield in three steps from glycol monomethyl ether glycol as starting material under mild conditions,is reported. Synthesis of intermediates 3-[2-(2-methoxyethoxy)- ethoxy]methylthiophene is reported for the first time.