+44 1625708989Synthesis and biological activity of 8-chloro-[1,2,4]triazolo [4,3-a]quinoxalines
Author(s): M. Suresh, P.Lavanya, D.Sudhakar, K.Vasu and C. Venkata Rao8-Chloro-1-substituted-[1,2,4]triazolo[4,3-a]quinox aline s 6 underwent facile condensation with various hydrocarbon derivatives in the presence of TEBAC in acetonitrile was refluxed and afforded corresponding 8-chloro-1,4-substituted-[1, 2,4]triazolo[4,3-a]quinoxaline derivatives 7a- j. Their chemical structures were characterized using IR, H 1 NMR and Mass spectral studies. All the above compounds were screened for anti-microbia l activity, anti-oxidant activity and their bioassay showed them to possess significant antimic robial activity and anti-oxidant activity.
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