Piperazine and morpholine:
Synthetic preview and pharmaceutical applications

Mohammed Al-Ghorbani; Bushra Begum A; Zabiulla; Mamatha S. V.; Shaukath Ara Khanum

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Piperazine and morpholine: Synthetic preview and pharmaceutical applications

Author(s): Mohammed Al-Ghorbani, Bushra Begum A, Zabiulla, Mamatha S. V. and Shaukath Ara Khanum

This review summarizes the in vitro and in vivo medicinal chemistry investigations for piperazine and morpholine analogues. Piperazine and morpholine nucleus show a broad spectrum of pharmaceutical applications, thus, in recent years, scientists has developed various new methods for the synthesis of their derivatives. This review shows current tendency in the piperazine and morpholine analogues synthesis and reveals their potent pharmacophoric activities.

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