Hepatoprotective Activity of Boerhavia diffusa against Paracetamol induced toxicity in rats

Venkatalakshmi. P; Eazhisai Vallabi. D; Netaji.S

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Hepatoprotective Activity of Boerhavia diffusa against Paracetamol induced toxicity in rats

Author(s): Venkatalakshmi. P, Eazhisai Vallabi. D and Netaji.S

The present study was designed to evaluate the hepato protective activity of Boerhavia diffusa against paracetamol induced hepatotoxic rats. Administration of paracetamol (3g/kg. b.wt.,) produced significant changes in the hepatocytes which was reflected in the altered parameters such as ALT, AST, GSH, Protein and Serum creatinine levels. Treatment with B.diffusa root extract (1g/kg. b.wt.,) produced remarkable changes and brought back the altered parameters to near normal, proving its hepato protective activity.

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