Anti inflammatory and wound healing activity of Curcuma aromatica salisb extract and its formulation

 

By Amit Kumar, Rajiv Chomwal, Praveen Kumar and Renu Sawal

 

Abstract

Anti-inflammatory and wound healing activity of topical application of Curcuma aromatica Salisb. rhizome extract and is cream formulations in Arachidonic acid -induced ear inflammation and excision wound model was confirmed in albino mice. The extraction of these rhizomes was carried out by ethanol. The ethanol extract and formulations exhibited significant anti- inflammatory activity in arachidonic acid - induced ear inflammation. It also showed significant wound healing activity in excision wound model. Thus, resultant anti-inflammatory activity might be due to effects on several mediators and arachidonic acid metabolism involving cyclo- oxygenase pathway resulting in prostaglandin synthesis.

Key Words: Anti-inflammatory, Arachidonic acid, Excision wound model.

 

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