Journal of Chemical and Pharmaceutical Research ( ISSN : 0975 – 7384 )
Anti inflammatory and wound healing activity of Curcuma aromatica salisb extract and its formulation
By Amit Kumar, Rajiv Chomwal, Praveen Kumar and Renu Sawal
Anti-inflammatory and wound healing activity of topical application of Curcuma aromatica Salisb. rhizome extract and is cream formulations in Arachidonic acid -induced ear inflammation
and excision wound model was confirmed in albino mice. The extraction of these rhizomes was
carried out by ethanol. The ethanol extract and formulations exhibited significant anti- inflammatory activity in arachidonic acid - induced ear inflammation. It also showed significant
wound healing activity in excision wound model. Thus, resultant anti-inflammatory activity
might be due to effects on several mediators and arachidonic acid metabolism involving cyclo-
oxygenase pathway resulting in prostaglandin synthesis.
Key Words: Anti-inflammatory, Arachidonic acid, Excision wound model.