+44 1625708989Spectrophotometric absorption factor method development and validation for estimation of Rosuvastatin Calcium and Telmisartan in solid dosage form
Author(s): Naman Doshi*, Avani Sheth, Tejas Patel, J B Dave and C N PatelA Simple, accurate and precise Spectrophotometric method have been developed for estimation of Rosuvastatin Calcium and Telmisartan by absorption factor method. Rosuvastatin calcium & Telmisartan exhibits lmax at 244 nm and 296 nm respectively. Quantitative estimation of Rosuvastatin Calcium was carried out by subtracting the absorption due to Telmisartan at 244 nm using experimentally calculated absorption factor. Beer's law was obeyed for Rosuvastatin Calcium and Telmisartan 2-7 �Ž�¼g/ml and 4-14 �Ž�¼g/ml respectively.The method was validated using ICH Guidelines. PDF